Journal of Emerging Trends in Engineering and Applied Sciences: Research Areas

Article Title: In-Vitro Anthelmintic Activity of Mucuna Pruriens (Dc) And Canarium Schweinfurthii (Engl) On Acaris Suum
by Okoli, B.J1, Ayo, R. G, Habila, J.D, Japhet S.L and Ndukwe, G. I

Abstract:
Mucuna pruriens and Canarium schweinfurthii used in traditional medicinal practices in Northern Nigeria, for the treatment of worms infestation were investigated. The in-vitro anthelmintic evaluation of the crude and solvent partitions extracts, on Pheretima posthuma and Ascaris suum (eggs and L2 stage) respectively. Showed that the hexane fraction (leaves and stem bark) of Canarium schweinfurthii and Mucuna pruriens (leaves) had ovicidal potency of (100.00 �0.33) at 80mg/ml. While the Chloroform fractions showed ovicidal activity of 98.20�0.12 and 98.20�0.12 80 mg/ml on the two plants respectively. The results of determination of larvicidal potency showed that the hexane fraction (0.06%) was the most potent, followed by the Chloroform fractions (0.1 and 0.2 % respectively). These results clearly justified the uses of these plants in the treatment of worms in ethno-medicinal practices.

Keywords: anthelmintic activity, mucuna pruriens, canarium schweinfurthii, pheretima posthuma, a. suum, eclodibility

Download full paper