Journal of Emerging Trends in Engineering and Applied Sciences: Research Areas

Article Title: Penicillins and Cephalosporins Against Microbic Aetiologies of Urinary Tract Infection; Concern to Public Health
by Ukaji, D. C., Eze, E. M and Ezeiruaku, F. C

Abstract:
The epidemiological survey of urinary tract infection in South-Eastern Nigeria was carried out between February 2006 and April 2007. Five hundred and three (503) subjects who had signs of UTI were enlisted for this study. With regard to their state of origin; 159 samples from Rivers, 102 from Bayelsa, 64 from Delta, 39 from Edo, 68 from Akwa Ibom and 71 from Cross River State were enlisted. The isolated microorganisms from the urinary tracts were subjected to susceptibility tests. The antimicrobial action of the antibacterials - Ciprofloxacin, gentamicin, Cefuroxime and Ampicillin were compared against the isolated organisms of Escherichia coli, Staphylococci, Proteus, Pseudomonas and klebsiella sp. There was statistical difference in their resistance (P<0.001) with near uniform resistance between ampicillin and cefuroxine. The present findings revealed a relatively high prevalence of resistance to Ampicillin and Cefuroxime in the South-Eastern Nigeria, underlining the need for urgent policy intervention before the situation escalates beyond control

Keywords: penicillins, cephalosporins, UTIs, public health

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