Journal of Emerging Trends in Engineering and Applied Sciences: Research Areas

Article Title: Prevalence of Prostate Cancer among Men with Elevated Prostate Specific Antigen (PSA) Level in Ikwerre Local Government Area of Rivers State, Nigeria
by Ezeiruaku, F.C., Eze, E. M., Ukaji, D. C. and Okoye, F. C

Abstract:
The prevalence of prostate cancer among men of age above 40 years has been on the increase and early detection help in suppressing the progression of the disease. The study was undertaken to report the prevalence of elevated prostate specific antigen (PSA) in Isiokpo, Omagwa, Ubima and Elele towns, all in Ikwerre Local Government Area of Rivers State, South of Nigeria. Using the Enzyme linked immuno sorbent assay (ELISA) method, a total of 1,325 men, aged 40 years and above (median age of 59 years) was assessed for PSA between February 2007 and March 2010. A total number of 126 men had PSA values above 4.0ng/ml, representing 9.51 percent. The subjects with elevated PSA values, an indication for risk of developing prostate cancer, were also subjected to ultrasound scanning, digital rectal examination (DRE) and biopsy examination. Out of 126 men with raised PSA level, 99 eventually went for the scan and biopsy examination. A total number of 41 were diagnosed of prostate cancer, representing 41.41 percent. The remaining 59.57 percent with PSA values above 4.0ng/ml therefore have risk of developing prostate cancer

Keywords: prevalence, prostate, prostate specific antigen, cancer, biopsy

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