Journal of Emerging Trends in Engineering and Applied Sciences: Research Areas

Article Title: The Hypoglycemic Effect of Aqueous Extract of the Anacardium occidentale Linn Leaves Grown in Nigeria on Normoglycemic Albino Rats
by Saidu, A. N., Mann, A., Balogun, S.

Abstract:
Extract of the Anacardium occidentale leaves is used in the traditional treatment of diabetic diseases. The hypoglycemic effect of leaves aqueous extract was investigated using normoglycemic albino rats. The leaves aqueous extract was found to contain phytochemicals such as alkaloids, saponins, flavonoids and tannins. The aqueous extract significantly lowered the blood glucose concentration in the normal rats (p>0.05). The extract produced about 33.7 % (305+_ 2.89 to 202 +_ 4.04) mg/dl. The serum triglyceride decreases by 48.28 % (435+_ 4.50 to 225+_ 1.50) mg/dl in the experimental rats. While serum total protein decreases by 18.41% (27.7 +_ 2.54 to 22.6 +_ 0.32) g/d and weight increase was 4.75 % (134.6 +_ 5.02 to 128.5 +_ 1.15) g. The result obtained indicated that the extract has a moderate hypoglycemic effect and may be used locally for the treatment of diabetes mellitus.

Keywords: anacardium occidentale, diabetes mellitus, hypoglycemic effect, blood glucose level

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